Antifungal activity of histatin-5 against non-albicans Candida species.

نویسندگان

  • H Nikawa
  • C Jin
  • H Fukushima
  • S Makihira
  • T Hamada
چکیده

Fungicidal effects of histatin-5 against 26 oral isolates belonging to 5 non-albicans Candida species were examined. Fifty microM of histatin-5 killed more than 95% of Candida tropicalis and Candida guilliermondii isolates and more than 90% of Candida parapsilosis and Candida krusei. However, Candida glabrata was less sensitive to the peptide (mean 62.9%). Our results, taken together, demonstrated that histatin-5 possessed the fungicidal activity against Candida species other than C. glabrata.

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عنوان ژورنال:
  • Oral microbiology and immunology

دوره 16 4  شماره 

صفحات  -

تاریخ انتشار 2001